Kelsey Grammer .... Dr. Frasier Winslow Crane
Jane Leeves .... Daphne Moon/Crane
David Hyde Pierce .... Dr. Niles Crane
Peri Gilpin .... Roz Doyle
John Mahoney .... Martin Crane

"Frasier" provides a weekly dose of the neuroses and tribulations suffered by an insecure and pompous psychiatrist, Dr. Frasier Crane, host of a Seattle radio advice show at KACL. The twice-divorced doctor's peaceful home life of fine cigars and haute cuisine was shattered when his gruff, ex-cop father, Martin, was injured in the line of duty and forced to move in with Frasier. Martin brought with him a semi-psychic, live-in home-care provider, Daphne Moon, his pesky Jack Russell terrier, Eddie, and a duct-taped recliner that clashes with Frasier's more aesthetically pleasing Eames and Wassily chairs. Their home is frequently visited by Frasier's snobbish and competitive brother, Niles, a fellow psychiatrist whose longtime romantic interest in Daphne was finally happily realized at the conclusion of Season 7. At work, his slightly jaded producer and man-hungry single parent Roz Doyle, supports Frasier. Some of the people who voice the callers to Frasier's radio program are often bigtime celebrities.