Stephen Collins
..... Reverend Eric Camden
Catherine Hicks
..... Annie Jackson-Camden
Barry Watson
..... Matt Camden (1996-2002, 2004-)
David Gallagher
..... Simon Camden (1996-2003, 2004-)
Jessica Biel
..... Mary Camden Rivera (1996-2001)
Beverley Mitchell
..... Lucy Camden Kinkirk
Mackenzie Rosman
..... Ruthie Camden
Adam LaVorgna
..... Robbie Palmer (2000-2002)
Lorenzo Brino
..... Sam Camden (1999-)
Nikolas Brino
..... David Camden (1999-)
Geoff Stults
..... Ben Kinkirk (2001-2003)
George Stults
..... Kevin Kinkirk (2002-)
Ashlee Simpson
..... Cecilia Smith (2002-2004)
Rachel Blanchard
..... Roxanne Richardson (2002-2004)
Jeremy London
..... Chandler Hampton (2002-2004)
Scotty Leavenworth
..... Peter Petrowski (2002-2004)
Chaz Lamar Shepherd
..... John Hamilton (1999-2001)
Happy
..... Herself
Tyler Hoechlin
..... Martin (2003-)
Myrinda Brino
..... Sam & David Camden (1999-2001) (uncredited)
Zachary Brino
..... Sam & David Camden (1999-2001) (uncredited)

The young adults on 7th Heaven are exposed to issues ranging from dating crises to teen suicide, sibling rivalry to gang violence. Storylines touched on such topics as the Holocaust, hate crimes, violence in schools, drug use, vandalism, drinking and driving, teen pregnancy and homelessness.

The series has received honors from the Parents Television Council, The Media Project's Shine Awards, Entertainment Industries Council's Prism Awards, Viewers Voice, Anti-Defamation League, Film Advisory Board, the Academy of Religious Broadcasting, Kids Choice Awards, Teen Choice Awards, Family Friendly Forum Awards and the TV Guide Awards